Autophagy Facilitates Metadherin-Induced Chemotherapy Resistance Through the AMPK/ATG5 Pathway in Gastric Cancer

Background/Aims: Metadherin (MTDH) is overexpressed in some malignancies and enhances drug resistance; however, its role in gastric cancer (GC) and the underlying mechanisms remain largely unexplored. Here, we explore the mechanism by which MTDH induces drug resistance in GC. Methods: We analysed th...

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書目詳細資料
發表在:Cellular Physiology and Biochemistry
Main Authors: Guoqing Pei, Meng Luo, Xiaochun Ni, Jugang Wu, Shoulian Wang, Yiwen Ma, Jiwei Yu
格式: Article
語言:英语
出版: Cell Physiol Biochem Press GmbH & Co KG 2018-04-01
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在線閱讀:https://www.karger.com/Article/FullText/488742