Reduced brain structural similarity is associated with maturation, neurobiological features, and clinical status in schizophrenia

Abstract Schizophrenia spectrum disorders (SSD) are characterized by atypical brain maturation, including alterations in structural similarity between regions. Using structural MRI data from 195 healthy controls (HC) and 352 individuals with SSD, we construct individual Morphometric INverse Divergen...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Natalia García-San-Martín, Richard AI Bethlehem, Patricia Segura, Agoston Mihalik, Jakob Seidlitz, Isaac Sebenius, Claudio Alemán-Morillo, Lena Dorfschmidt, Golia Shafiei, Sarah E. Morgan, Miguel Ruiz-Veguilla, Rosa Ayesa-Arriola, Javier Vázquez-Bourgon, Bratislav Misic, John Suckling, Benedicto Crespo-Facorro, Rafael Romero-García
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-10-01
Online Access:	https://doi.org/10.1038/s41467-025-63792-6