Bending and Twisting the Embryonic Heart: A Computational Model for C-Looping Based on Realistic Geometry

The morphogenetic process of cardiac looping transforms the straight heart tube into a curved tube that resembles the shape of the future four-chambered heart. Although great progress has been made in identifying the molecular and genetic factors involved in looping, the physical mechanisms that dri...

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Bibliographic Details

Published in:	Frontiers in Physiology
Main Authors:	Yunfei eShi, Jiang eYao, Jonathan M Young, Judy A Fee, Renato ePerucchio, Larry A Taber
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-08-01
Subjects:	Biomechanics Chick Embryo Morphogenesis finite-element modeling Cardiac Looping
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00297/full