Lactate Dehydrogenase Inhibitors Suppress <i>Borrelia burgdorferi</i> Growth In Vitro

<i>Borrelia burgdorferi</i>, the causative agent of Lyme disease, has a highly reduced genome and relies heavily on glycolysis for carbon metabolism. As such, established inhibitors of lactate dehydrogenase (LDH) were evaluated in cultures to determine the extent of their impacts on <...

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出版年:	Pathogens
主要な著者:	Adam Lynch, Patrick Pearson, Sergey N. Savinov, Andrew Y. Li, Stephen M. Rich
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2023-07-01
主題:	<i>Borrelia burgdorferi</i> LDH inhibitors lactate dehydrogenase gossypol
オンライン･アクセス:	https://www.mdpi.com/2076-0817/12/7/962