Comparison of gepant effects at therapeutic plasma concentrations: connecting pharmacodynamics and pharmacokinetics

Abstract Background Orally administered second-generation gepants are effective for the treatment of migraine. The intranasal administration of the third-generation gepant zavegepant might have additional benefits including a rapid onset of action, but it is not clear yet to which extent this has cl...

Full description

Bibliographic Details
Published in:The Journal of Headache and Pain
Main Authors: Deirdre M. Boucherie, Ruben Dammers, Arnaud Vincent, A. H. Jan Danser, Antoinette MaassenVanDenBrink
Format: Article
Language:English
Published: BMC 2024-08-01
Subjects:
Online Access:https://doi.org/10.1186/s10194-024-01846-8