Enhancing Gene Delivery in NB-4 Cells: Overcoming Transduction and Selection Challenges

Efficient gene transduction and cell viability are critical factors in genetic manipulation for research and therapeutic purposes. In this study, we explored the challenges associated with transducing the NB-4 cell line, a well-established model for acute promyelocytic leukemia (APL), using lentivir...

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Bibliographic Details

Published in:	Cells
Main Authors:	Stefano Leto, Sonakshi Gehlot, Bhavwanti Sheth, Stefano Ratti, Lucia Manzoli, Nullin Divecha, Roberta Fiume
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Subjects:	gene transduction NB-4 leukemia cells viral vector engineering
Online Access:	https://www.mdpi.com/2073-4409/13/22/1849