Development and Validation of an LC–MS/MS Method for Quantifying Gabapentin in Plasma: Application to a Pharmacokinetic Study in Cats

Gabapentin (GBP), a γ-aminobutyric acid analogue used for neuropathic pain and epilepsy, can reduce cat stress and improve veterinary exam compliance. A sensitive LC-MS/MS assay was established and rigorously validated for quantifying GBP in feline plasma. The method employed acetonitrile-mediated p...

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出版年:	Animals
主要な著者:	Feifei Zhao, Changcheng Lin, Yunying Wu, Xinyue Luo, Ning Han, Wenguang Xiong, Zhenling Zeng
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2025-03-01
主題:	gabapentin LC-MS/MS cat plasma pharmacokinetics
オンライン･アクセス:	https://www.mdpi.com/2076-2615/15/7/950