Single-cell RNA-sequencing analysis of immune and mesenchymal cell crosstalk in the developing enthesis

Abstract Autoimmunity underlies many painful disorders, such as enthesopathies, which localize to the enthesis. From infiltration of the synovium and axial skeleton by B cells, to disturbances in the ratio of M1/M2 enthesis macrophages, to CD8 + T cell mediated inflammation, autoimmune dysregulation...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Valia P. Leifer, Fei Fang, Lee Song, Jieon Kim, John F. Papanikolaou, Joanna Smeeton, Stavros Thomopoulos
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-11-01
Subjects:	Enthesis development Mineralization Immune cells Mesenchymal cells Single-cell RNA-sequencing Cell–cell crosstalk
Online Access:	https://doi.org/10.1038/s41598-024-77958-7