Risk assessment of relapse by lineage-specific monitoring of chimerism in children undergoing allogeneic stem cell transplantation for acute lymphoblastic leukemia

Allogeneic hematopoietic stem cell transplantation is required as rescue therapy in about 20% of pediatric patients with acute lymphoblastic leukemia. However, the relapse rates are considerable, and relapse confers a poor outcome. Early assessment of the risk of relapse is therefore of paramount im...

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Bibliographic Details
Published in:Haematologica
Main Authors: Sandra Preuner, Christina Peters, Ulrike Pötschger, Helga Daxberger, Gerhard Fritsch, Rene Geyeregger, André Schrauder, Arend von Stackelberg, Martin Schrappe, Peter Bader, Wolfram Ebell, Cornelia Eckert, Peter Lang, Karl-Walter Sykora, Johanna Schrum, Bernhard Kremens, Karoline Ehlert, Michael H. Albert, Roland Meisel, Anita Lawitschka, Georg Mann, Renate Panzer-Grümayer, Tayfun Güngör, Wolfgang Holter, Brigitte Strahm, Bernd Gruhn, Ansgar Schulz, Wilhelm Woessmann, Thomas Lion
Format: Article
Language:English
Published: Ferrata Storti Foundation 2016-06-01
Online Access:https://haematologica.org/article/view/7740