Biofabrication of prevascularized spheroids for bone tissue engineering by fusion of microvascular fragments with osteoblasts

IntroductionSpheroids are promising building blocks for scaffold-free bone tissue engineering. Their rapid vascularization is of major importance to guarantee their survival after transplantation. To achieve this, we herein introduce the biofabrication of prevascularized spheroids by fusion of adipo...

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Bibliographic Details

Published in:	Frontiers in Bioengineering and Biotechnology
Main Authors:	Selina Wrublewsky, Jessica Schultz, Tekoshin Ammo, Caroline Bickelmann, Wolfgang Metzger, Thomas Später, Tim Pohlemann, Michael D. Menger, Matthias W. Laschke
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	microvascular fragments osteoblasts spheroid bone tissue engineering vascularization
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2024.1436519/full