A cytoprotective role for optineurin during mycobacterial infection of macrophages

Autophagy has emerged as a critical innate immune mechanism for host elimination of intracellular pathogens, however, the role of the autophagy receptor Optineurin during mycobacterial infection is not fully understood. To address this lacuna, we infected bone marrow-derived macrophages (BMDMs) deri...

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Bibliographic Details

Published in:	Biochemistry and Biophysics Reports
Main Authors:	Gopalakrishna Ramachandran, Chaitanya Veena Yeruva, Ghanshyam Swarup, Tirumalai R. Raghunand
Format:	Article
Language:	English
Published:	Elsevier 2024-07-01
Subjects:	Optineurin Mycobacteria Macrophages Autophagy Cell death Cytoprotectivity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405580824000360