Systemic immune-inflammation index: a key biomarker guiding personalized adjuvant chemotherapy in intrahepatic cholangiocarcinoma

BackgroundIntrahepatic cholangiocarcinoma (ICC) is a highly aggressive primary liver malignancy, with poor long-term outcomes even after curative-intent resection. Postoperative adjuvant chemotherapy (pAC) is increasingly used, but its benefit is not uniform across all patients. The systemic immune-...

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Bibliographic Details
Published in:Frontiers in Oncology
Main Authors: Xin Yin, Yanjiang Yin, Wenzhuo Li, Jinliang Tong, Yi Liu, Jianping Chang, Jindong Ma, Yaoyu Xie, Xin Li, Hossein Mehrabanidil, Xiao Chen, Yefan Zhang, Jianqiang Cai, Caiyun Li, Bowen Xu, Zhiyu Li, Xinyu Bi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-10-01
Subjects:
intrahepatic cholangiocarcinoma
systemic immune-inflammation index
adjuvant chemotherapy
prognosis
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1702336/full

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https://www.frontiersin.org/articles/10.3389/fonc.2025.1702336/full

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