1,6-Nucleophilic Di- and Trifluoromethylation of <i>para</i>-Quinone Methides with Me<sub>3</sub>SiCF<sub>2</sub>H/Me<sub>3</sub>SiCF<sub>3</sub> Facilitated by CsF/18-Crown-6

The direct 1,6-nucleophilic difluoromethylation, trifluoromethylation, and difluoroalkylation of <i>para</i>-quinone methides (<i>p</i>-QMs) with Me<sub>3</sub>SiRf (Rf = CF<sub>2</sub>H, CF<sub>3</sub>, CF<sub>2</sub>CF<sub&...

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Bibliographic Details
Published in:Molecules
Main Authors: Dingben Chen, Ling Huang, Mingyu Liang, Xiaojing Chen, Dongdong Cao, Pan Xiao, Chuanfa Ni, Jinbo Hu
Format: Article
Language:English
Published: MDPI AG 2024-06-01
Subjects:
difluoromethylation
trifluoromethylation
Me<sub>3</sub>SiCF<sub>2</sub>H/Me<sub>3</sub>SiCF<sub>3</sub>
1,6-nucleophilic addition
CsF/18-crown-6
Online Access:https://www.mdpi.com/1420-3049/29/12/2905

Internet

https://www.mdpi.com/1420-3049/29/12/2905

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