Rare subungual amelanotic melanoma presenting as prolonged swelling and exudation after trauma: case report and literature review

BackgroundSubungual amelanotic melanoma (SAM) poses significant diagnostic challenges due to its rarity and nonspecific clinical manifestations, such as nail dystrophy or indurated plaque.Case presentationWe present the case of a 60-year-old woman with a three-year history of recurrent serous draina...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Lin An, Ziyu Liu, Xiangru Chen, Yuxi Jia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	subungual amelanotic melanoma trauma post-traumatic immunosuppression differential diagnosis immunohistochemistry
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1661698/full