Early assessment and treatment of ventricular remodeling in vivo via a targeted ultrasonic molecular probe loaded with oxygen and cholecystokinin

Abstract Early identification and treatment of ventricular remodeling (VR) are crucial for delaying the progression of heart failure after myocardial infarction. This study aims to develop a dual-responsive phase-shift molecular probe loaded with a cholecystokinin octapeptide (CCK-8) and oxygen, whi...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Can Wang, Hongfeng Cheng, Xiaoying Dong, Yue Zhan, Ying Liu, Nianhong Wu, Rui Tang, Hongye He, Yuting Cao, Liping Yang, Jianli Ren, Xingsheng Li, Pan Li
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Subjects:	Low-intensity focused ultrasound Ventricular remodeling Molecular imaging probe Supersaturated oxygen therapy Cholecystokinin octapeptide
Online Access:	https://doi.org/10.1186/s12951-025-03183-7