Targeting ROR2 homooligomerization disrupts ROR2-dependent signaling and suppresses stem-like cell properties of human breast adenocarcinoma

Summary: Breast cancer stem-like cells (CSCs) are enriched following treatment with chemotherapy, and posited as having a high level of plasticity and enhanced tumor-initiation capacity, which can enable cancer relapse. Here, we show that such features are shared by breast cancer (BCA) cells that ex...

詳細記述

書誌詳細

出版年:	iScience
主要な著者:	Feng Leng, Jiajia Huang, Liufeng Wu, Jianchao Zhang, Xinxin Lin, Ruhuan Deng, Jinhang Zhu, Zhen Li, Zhenghao Li, Yimeng Wang, Han Zhang, Desheng Lu, Thomas J. Kipps, Suping Zhang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2025-01-01
主題:	Stem cell plasticity Molecular interaction Cancer
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2589004224028165