Modulation of microRNA activity by semi-microRNAs (smiRNAs)

The ribonuclease Dicer plays a central role in the microRNA pathway by catalyzing the formation of 19 to 24-nucleotide (nt) long microRNAs. Subsequently incorporated into Ago2 effector complexes, microRNAs are known to regulate messenger RNA (mRNA) translation. Whether shorter RNA species derived fr...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Isabelle ePlante, Hélène ePlé, Patricia eLandry, Preethi Herat Gunaratne, Patrick eProvost
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2012-06-01
Subjects:	microRNA non-coding RNA dicer Argonaute 2 RNA silencing
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00099/full