FOXO3-induced microRNA-128-3p promotes the progression of spinal cord injury in mice via regulating NLRP3 inflammasome-mediated pyroptosis

BackgroundSpinal cord injury (SCI) remains a severe condition with an extremely high disability rate and complex pathophysiologic mechanisms. Pyroptosis, an inflammatory form of cell death triggered by certain inflammasomes, has a key role in a variety of inflammatory diseases, including SCI. Howeve...

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發表在:	Frontiers in Immunology
Main Authors:	Shuo Yang, Yunzhi Guan, Chaojun Zheng, Xinlei Xia, Xiaosheng Ma, Jianyuan Jiang
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2025-02-01
主題:	MiR-128-3p NLRP3-mediated pyroptosis ROS neuroinflammation spinal cord injury
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526721/full