Silence of HOTAIR promotes osteogenic differentiation and accelerates distraction osteogenesis by mediating FTO ubiquitination

Background: Distraction osteogenesis(DO) is a valuable bone regeneration technique, yet its prolonged consolidation phase often entails pain, high costs, infection risks, and lifestyle disruptions. Finding adjunctive approaches to shorten treatment duration is thus of clinical significance. Long non...

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Bibliographic Details

Published in:	Journal of Orthopaedic Translation
Main Authors:	Xiao-min Wu, Yong-xin Mai, Yong-fa Wen, Zhi-peng Li, Yu-xin Sun, Jun-jing Chen, Fengzhen Meng, feng-xiang Pang, Huai-ming Li, Yu Pan, Jin-fang Zhang, Xiao-hua Pan
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	Distraction osteogenesis FTO HOTAIR Osteogenesis Ubiquitination
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X24001608