Variants of sequence family B Thermococcus kodakaraensis DNA polymerase with increased mismatch extension selectivity.

Fidelity and selectivity of DNA polymerases are critical determinants for the biology of life, as well as important tools for biotechnological applications. DNA polymerases catalyze the formation of DNA strands by adding deoxynucleotides to a primer, which is complementarily bound to a template. To...

Full description

Bibliographic Details
Published in:PLoS ONE
Main Authors: Claudia Huber, Andreas Marx
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Online Access:http://europepmc.org/articles/PMC5568139?pdf=render