Senolytic treatment diminishes microglia and decreases severity of experimental autoimmune encephalomyelitis

Abstract Background The role of senescence in disease contexts is complex, however there is considerable evidence that depletion of senescent cells improves outcomes in a variety of contexts particularly related to aging, cognition, and neurodegeneration. Much research has shown previously that infl...

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出版年:	Journal of Neuroinflammation
主要な著者:	Sienna S. Drake, Aliyah Zaman, Christine Gianfelice, Elizabeth M.-L. Hua, Kali Heale, Elia Afanasiev, Wendy Klement, Jo Anne Stratton, Alexandre Prat, Stephanie Zandee, Alyson E. Fournier
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-11-01
主題:	Microglia Multiple sclerosis Senescence Neuroinflammation Experimental autoimmune encephalomyelitis Senolytics
オンライン･アクセス:	https://doi.org/10.1186/s12974-024-03278-2