Evaluation of uNGAL and TIMP-2*IGFBP7 as early biomarkers of Acute Kidney Injury in Caucasian term and preterm neonates: a prospective observational cohort study

Abstract Background Early diagnosis of Acute Kidney Injury (AKI) in neonates is a complex challenge. Novel urinary biomarkers such as uNGAL and TIMP-2*IGFBP7 may be helpful for predicting AKI earlier than changes in serum creatinine (sCr) and urinary output (UOP) in the neonatal period. uNGAL is a m...

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Bibliographic Details

Published in:	Italian Journal of Pediatrics
Main Authors:	Raffaella Panza, Annalisa Schirinzi, Maria Elisabetta Baldassarre, Rossella Caravita, Riccardo Laterza, Elisa Mascolo, Federica Malerba, Francesca Di Serio, Nicola Laforgia
Format:	Article
Language:	English
Published:	BMC 2025-03-01
Subjects:	Acute kidney injury [Mesh] Biomarkers [Mesh] Neonates [Mesh] NGAL TIMP-2*IGFBP7 Preterm birth [Mesh]
Online Access:	https://doi.org/10.1186/s13052-025-01899-8