Integrins linked kinase and focal adhesion kinase as the key signaling mediators of vascular mimicry in metastatic breast tumor cells

Abstract Objective In highly aggressive malignant cancers including breast cancer, vasculogenic mimicry (VM) is the potential of tumor cells to generate a vascular channel network for delivering blood to tumor cells. Detection of genes involved in this process is critical to designing targeted thera...

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Bibliographic Details

Published in:	BMC Research Notes
Main Authors:	Mohammad Kamalabadi-Farahani, Vahid Kia, Sadegh Dylami, Amir Atashi
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Subjects:	Breast cancer Metastasis Vascular mimicry Integrins linked kinase (ILK) Focal adhesion kinase (FAK)
Online Access:	https://doi.org/10.1186/s13104-024-06953-y