The role of podocyte injury in the pathogenesis of Fabry disease nephropathy

Abstract Renal involvement is one of the most severe morbidities of Fabry disease (FD), a multisystemic lysosomal storage disease with an X-linked inheritance pattern. It results from pathogenic variants in the GLA gene (Xq22.2), which encodes the production of alpha-galactosidase A (α-Gal), respons...

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Bibliographic Details

Published in:	Brazilian Journal of Nephrology
Main Authors:	José Tiburcio do Monte Neto, Gianna Mastroianni Kirsztajn
Format:	Article
Language:	English
Published:	Sociedade Brasileira de Nefrologia 2024-07-01
Subjects:	Fabry Disease Podocyte Glomerular Filtration Barrier Autophagy Renal Insufficiency Chronic
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002024000300403&lng=en&tlng=en