Erlotinib Treatment in Colorectal Cancer Suppresses Autophagy Based on <i>KRAS</i> Mutation

The <i>KRAS</i> gene is mutated in approximately 45% of colorectal cancer patients. There are currently very few targeted treatments or therapies equipped to directly inhibit <i>KRAS</i> due to its unusual structural intricacies. Erlotinib, an EGFR inhibitor, has previously b...

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Bibliographic Details
Published in:Current Issues in Molecular Biology
Main Authors: Alexander Siegman, Aaron Shaykevich, Danbee Chae, Isaac Silverman, Sanjay Goel, Radhashree Maitra
Format: Article
Language:English
Published: MDPI AG 2024-07-01
Subjects:
Online Access:https://www.mdpi.com/1467-3045/46/7/447