Biology of Germinal Center B Cells Relating to Lymphomagenesis
The germinal center (GC) reaction is a key feature of adaptive humoral immunity. GCs represent the site where mature B cells refine their B-cell receptor (BCR) and are selected based on the newly acquired affinity for the antigen. In the GC, B cells undergo multiple cycles of proliferation, BCR remo...
| Published in: | HemaSphere |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-06-01
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| Online Access: | http://journals.lww.com/10.1097/HS9.0000000000000582 |