mRNA extracted from frozen buffy coat samples stored long term in tubes with no RNA preservative shows promise for downstream sequencing analyses.

Transcriptomics is an important OMICs method that is often unavailable in biobank research. Frozen blood samples are routinely collected and stored in medical biobanks, but transcriptional studies have been limited due to technical difficulties of extracting high-quality RNA from blood frozen in sta...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Erik Bovinder Ylitalo, Linda Vidman, Sophia Harlid, Bethany Van Guelpen
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Online Access:	https://doi.org/10.1371/journal.pone.0318834