Thiopurine S-methyltransferase activity in Nigerians: phenotypes and activity reference values

Abstract Objectives This study assessed the activity of thiopurine S-methyltransferase (TPMT) in Nigerians with a view to providing data on susceptibility to thiopurine toxicity, and as well generate reference activity values for clinical use. Results TPMT activity, expressed as the amount of 6MMP i...

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Bibliographic Details

Published in:	BMC Research Notes
Main Authors:	Ayorinde Adehin, Oluseye O. Bolaji
Format:	Article
Language:	English
Published:	BMC 2018-02-01
Subjects:	TPMT Metabolic phenotypes Thiopurine toxicity Nigerians
Online Access:	http://link.springer.com/article/10.1186/s13104-018-3237-5