Aging-dependent changes in rat heart mitochondrial glutaredoxins—Implications for redox regulation

Clinical and animal studies have documented that hearts of the elderly are more susceptible to ischemia/reperfusion damage compared to young adults. Recently we found that aging-dependent increase in susceptibility of cardiomyocytes to apoptosis was attributable to decrease in cytosolic glutaredoxin...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Redox Biology
المؤلفون الرئيسيون:	Xing-Huang Gao, Suparna Qanungo, Harish V. Pai, David W. Starke, Kelly M. Steller, Hisashi Fujioka, Edward J. Lesnefsky, Janos Kerner, Mariana G. Rosca, Charles L. Hoppel, John J. Mieyal
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2013-01-01
الموضوعات:	Aging Glutaredoxin Glutathionylation Iron–sulfur cluster Mitochondria Reactive oxygen species (ROS) Redox regulation
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2213231713000797