Pharmacokinetics, Bioavailability, and Tissue Distribution of the Kirsten Rat Sarcoma Inhibitor Adagrasib in Rats Using UPLC-MS/MS

Pan Lei,1,2 Wanying Shen,2 Huijuan Tang,2 Li You,2 Guoyi Chen,2 Yijun Tang,1 Wei Lu3 1Hubei Key Laboratory of Embryonic Stem Cell Research, Taihe Hospital, Hubei University of Medicine, Shiyan, People’s Republic of China; 2Hubei Hongshan Laboratory, College of Biomedicine and Health, College of Life...

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Published in:	Drug Design, Development and Therapy
Main Authors:	Lei P, Shen W, Tang H, You L, Chen G, Tang Y, Lu W
Format:	Article
Language:	English
Published:	Dove Medical Press 2024-01-01
Subjects:	adagrasib uplc-ms/ms pharmacokinetics tissue distribution
Online Access:	https://www.dovepress.com/pharmacokinetics-bioavailability-and-tissue-distribution-of-the-kirste-peer-reviewed-fulltext-article-DDDT