Emodin induced hepatic steatosis in BALb/c mice by modulating the gut microbiota composition and fatty acid metabolism

IntroductionThe aim of this study is to examine the physiological effects of emodin on intestinal microorganisms and the liver in the BALb/c mice.Method and ResultsFollowing an 8-week administration of emodin at doses of 25, 50, and 100 mg/kg/day,pathological analyses revealed that emodin significan...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Xinhua Xia, Xueling He, Jinzhou Huang, Xuyang Hou, Chen Lin, Yaxiong Liu, Mei Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-12-01
Subjects:	emodin polygoni multiflori radix hepatic steatosis gut microbiota FFAs non-targeted metabolomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1516272/full