Tail Anchored protein insertion mediated by CAML and TRC40 links to neuromuscular function in mice.

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and progressive bulbar palsy, involve loss of muscle control resulting from death of motor neurons. Although the exact pathogenesis of these syndromes remains elusive, many are caused by genetically inherited mutations. Thus, it is v...

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Bibliographic Details

Published in:	PLoS Genetics
Main Authors:	Ying Zhang, Lihong He, Justin Gundelach, Anjie Ge, Helena Edlund, Stefan Norlin, Richard J Bram
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Online Access:	https://doi.org/10.1371/journal.pgen.1011547