Identification of the novel FOXP3-dependent Treg cell transcription factor MEOX1 by high-dimensional analysis of human CD4+ T cells

CD4+ T cells play a central role in the adaptive immune response through their capacity to activate, support and control other immune cells. Although these cells have become the focus of intense research, a comprehensive understanding of the underlying regulatory networks that orchestrate CD4+ T cel...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Kevin Baßler, Lisa Schmidleithner, Mehrnoush Hadaddzadeh Shakiba, Tarek Elmzzahi, Maren Köhne, Stefan Floess, Rebekka Scholz, Naganari Ohkura, Timothy Sadlon, Kathrin Klee, Anna Neubauer, Shimon Sakaguchi, Simon C. Barry, Jochen Huehn, Lorenzo Bonaguro, Thomas Ulas, Marc Beyer
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-07-01
Subjects:	Treg cells MEOX1 Foxp3 regulatory T cells human CD4
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1107397/full