P- 43 PIRFENIDONE PREVENTS NEOPLASTIC LESIONS DEVELOPMENT BY OXIDATIVE, FIBROGENIC, ANTIPROLIFERATIVE AND EPIGENETIC MECHANISMS REGULATION IN A MODEL OF CHEMICAL HEPATOCARCINOGENESIS

Introduction and Objectives: Hepatocellular carcinoma (HCC) is the most frequent hepatic neoplasia, where oxidative, fibrogenic, proliferative, and epigenetic processes are altered. Pirfenidone (PFD) has been shown to have important hepatoprotective properties. However, its efficacy in HCC developme...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Annals of Hepatology
المؤلفون الرئيسيون:	Hipólito Otoniel Miranda-Roblero, Hugo Christian Monroy-Ramírez, Marina Galicia-Moreno, Ana Sandoval-Rodriguez, Arturo Santos, Juan Armendáriz-Borunda
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2023-03-01
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S1665268123000492