Genetics of chloroquine-resistant malaria: a haplotypic view

The development and rapid spread of chloroquine resistance (CQR) in Plasmodium falciparum have triggered the identification of several genetic target(s) in the P. falciparum genome. In particular, mutations in the Pfcrt gene, specifically, K76T and mutations in three other amino acids in the region...

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Bibliographic Details
Published in:Memorias do Instituto Oswaldo Cruz
Main Authors: Gauri Awasthi, Aparup Das
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2013-12-01
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000800947&lng=en&tlng=en