Effects of the therapy shift from cortisone acetate to modified-release hydrocortisone in a group of patients with adrenal insufficiency

ObjectivePatients with adrenal insufficiency (AI) may be exposed to supraphysiological glucocorticoids levels during standard treatment with cortisone acetate (CA) or immediate-release hydrocortisone (IR-HC). Recent studies, predominantly including patients in IR-HC treatment, suggested that modifie...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Sofia Frigerio, Giulia Carosi, Emanuele Ferrante, Elisa Sala, Elisa Polledri, Silvia Fustinoni, Bruno Ambrosi, Iacopo Chiodini, Giovanna Mantovani, Valentina Morelli, Maura Arosio
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-01-01
Subjects:	adrenal insufficiency salivary cortisol Addison disease hydrocortisone modified-release hydrocortisone (MRH)
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2023.1093838/full