Secretion of IL-1β From Monocytes in Gout Is Redox Independent

The pro-inflammatory cytokine interleukin-1β (IL-1β) plays important roles in immunity but is also implicated in autoimmune disease. The most well-established mechanism of IL-1β secretion is via activation of the NOD-like receptor family pyrin domain containing-3 (NLRP3) inflammasome which requires...

Full description

Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Ben M. Alberts, Connor Bruce, Kolitha Basnayake, Pietro Ghezzi, Kevin A. Davies, Lisa M. Mullen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Subjects:
IL-1β
gout
chronic kidney disease
NLRP3 inflammasome
antioxidant capacity
redox regulation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00070/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00070/full

Similar Items