Corilagin alleviates atherosclerosis by inhibiting NLRP3 inflammasome activation via the Olfr2 signaling pathway in vitro and in vivo

IntroductionAtherosclerosis, a leading cause of global cardiovascular mortality, is characterized by chronic inflammation. Central to this process is the NOD-like receptor pyrin domain containing 3 (NLRP3) inflammasome, which significantly influences atherosclerotic progression. Recent research has...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Jinqian Mao, Yunfei Chen, Qiushuo Zong, Cuiling Liu, Jiao Xie, Yujie Wang, David Fisher, Nguyen Thi Thu Hien, Khrystyna Pronyuk, Erkin Musabaev, Yiqing Li, Lei Zhao, Yiping Dang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-05-01
Subjects:	atherosclerosis inflammation Olfr2 NLRP3 inflammasome corilagin therapeutic strategies
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1364161/full