Novel insights into histone lysine methyltransferases in cancer therapy: From epigenetic regulation to selective drugs

The reversible and precise temporal and spatial regulation of histone lysine methyltransferases (KMTs) is essential for epigenome homeostasis. The dysregulation of KMTs is associated with tumor initiation, metastasis, chemoresistance, invasiveness, and the immune microenvironment. Therapeutically, t...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Journal of Pharmaceutical Analysis
المؤلفون الرئيسيون:	Qili Liao, Jie Yang, Shengfang Ge, Peiwei Chai, Jiayan Fan, Renbing Jia
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2023-02-01
الموضوعات:	Cancer Epigenetics Histone lysine methyltransferase Epigenetic inhibitors Combined therapeutic strategy Clinical application
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2095177922001228