ABCC6 deficiency promotes dyslipidemia and atherosclerosis

Abstract ABCC6 deficiency promotes ectopic calcification; however, circumstantial evidence suggested that ABCC6 may also influence atherosclerosis. The present study addressed the role of ABCC6 in atherosclerosis using Ldlr −/− mice and pseudoxanthoma elasticum (PXE) patients. Mice lacking the Abcc6...

Full description

Bibliographic Details
Published in:Scientific Reports
Main Authors: Christopher Brampton, Viola Pomozi, Li-Hsieh Chen, Ailea Apana, Sara McCurdy, Janna Zoll, William A. Boisvert, Gilles Lambert, Daniel Henrion, Simon Blanchard, Sheree Kuo, Georges Leftheriotis, Ludovic Martin, Olivier Le Saux
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Online Access:https://doi.org/10.1038/s41598-021-82966-y