Evidence for a transgenerational mutational signature from ionizing radiation exposure in humans

Abstract The existence of transgenerational effects of radiation exposure on the human germline remains controversial. Evidence for transgenerational biomarkers are of particular interest for populations, who have been exposed to higher than average levels of ionizing radiation (IR). This study inve...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Fabian Brand, Hannah Klinkhammer, Alexej Knaus, Manuel Holtgrewe, Leonie Weinhold, Dieter Beule, Kerstin Ludwig, Prachi Kothiyal, George Maxwell, Markus Noethen, Matthias Schmid, Karl Sperling, Peter Krawitz
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Online Access:https://doi.org/10.1038/s41598-025-07030-5