ANO1‐Mediated Inhibition of Cancer Ferroptosis Confers Immunotherapeutic Resistance through Recruiting Cancer‐Associated Fibroblasts

Abstract The application of immunotherapy in gastrointestinal (GI) cancers remains challenging because of the limited response rate and emerging therapeutic resistance. Combining clinical cohorts, multi‐omics study, and functional/molecular experiments, it is found that ANO1 amplification or high‐ex...

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发表在:	Advanced Science
Main Authors:	Fangli Jiang, Keren Jia, Yang Chen, Congcong Ji, Xiaoyi Chong, Zhongwu Li, Feilong Zhao, Yuezong Bai, Sai Ge, Jing Gao, Xiaotian Zhang, Jian Li, Lin Shen, Cheng Zhang
格式:	文件
语言:	英语
出版:	Wiley 2023-08-01
主题:	ANO1 cancer‐associated fibroblasts ferroptosis gastrointestinal cancers immunotherapeutic resistance
在线阅读:	https://doi.org/10.1002/advs.202300881