STAT3 promotes NLRP3 inflammasome activation by mediating NLRP3 mitochondrial translocation

Abstract Recognition of the translocation of NLRP3 to various organelles has provided new insights for understanding how the NLRP3 inflammasome is activated by different stimuli. Mitochondria have already been demonstrated to be the site of NLRP3 inflammasome activation, and the latest research sugg...

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Bibliographic Details
Published in:Experimental and Molecular Medicine
Main Authors: Ling Luo, Fupeng Wang, Xueming Xu, Mingliang Ma, Guangyan Kuang, Yening Zhang, Dan Wang, Wei Li, Ningjie Zhang, Kai Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2024-09-01
Online Access:https://doi.org/10.1038/s12276-024-01298-9