Herbal formula xuling-jiangu improves bone metabolic balance in rats with ovariectomy-induced osteoporosis via the gut-bone axis

IntroductionThe XuLing JianGu recipe (XLJGR) is an empirical traditional Chinese medicine formula used for the treatment of osteoporosis. This study aims to explore the effects of XLJGR on the intestinal microbiota composition and endogenous metabolites in ovariectomized (OVX) rats.MethodsAn OVX rat...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Juan Chen, Szetuen Ng, Pengchao Xu, Sainan Chen, Shengqiang Li, Xuan Chen, Lihua Xie, Jirong Ge
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Subjects:	XuLing JianGu recipe osteoporosis metagenomic metabolomic gut-bone axis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1505231/full