[99mTc]Tc-Sestamibi Bioaccumulation Can Induce Apoptosis in Breast Cancer Cells: Molecular and Clinical Perspectives

The aim of this study was to investigate the possible role of [99mTc]Tc-Sestamibi in the regulation of cancer cell proliferation and apoptosis. To this end, the in vivo values of [99mTc]Tc-Sestamibi uptake have been associated with the in-situ expression of both Ki67 and caspase-3. For in vitro inve...

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Bibliographic Details

Published in:	Applied Sciences
Main Authors:	Nicoletta Urbano, Manuel Scimeca, Rita Bonfiglio, Alessandro Mauriello, Elena Bonanno, Orazio Schillaci
Format:	Article
Language:	English
Published:	MDPI AG 2021-03-01
Subjects:	99mTc-sestamibi breast-specific γ imaging breast cancer apoptosis theragnostic
Online Access:	https://www.mdpi.com/2076-3417/11/6/2733