Heterologous Production of a Novel Cyclic Peptide Compound, KK-1, in Aspergillus oryzae

A novel cyclic peptide compound, KK-1, was originally isolated from the plant-pathogenic fungus Curvularia clavata. It consists of 10 amino acid residues, including five N-methylated amino acid residues, and has potent antifungal activity. Recently, the genome-sequencing analysis of C. clavata was c...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Akira Yoshimi, Sigenari Yamaguchi, Tomonori Fujioka, Kiyoshi Kawai, Katsuya Gomi, Masayuki Machida, Keietsu Abe
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-04-01
Subjects:	antifungal activity Aspergillus oryzae gene cluster heterologous production non-ribosomal peptide
Online Access:	http://journal.frontiersin.org/article/10.3389/fmicb.2018.00690/full