Compensator-based small animal IMRT enables conformal preclinical dose painting: application to tumor hypoxia

Abstract Techniques for preclinical intensity modulated radiation therapy are being developed to improve translation by replicating the clinical paradigm. This study presents the first treatment planning comparison between small animal IMRT (SA-IMRT) and three-dimensional conformal radiotherapy (CRT...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Jordan M. Slagowski, Erik Pearson, Rajit Tummala, Gage Redler, Daniela Olivera Velarde, Boris Epel, Howard J. Halpern, Bulent Aydogan
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Online Access:https://doi.org/10.1038/s41598-025-08762-0