An Unexpected Result of Base-Promoted Rearrangement of 4a-Acetyl-8a-hydroxydecahydroquinazoline-2-thione
Treatment of 4a-acetyl-8a-hydroxydecahydroquinazoline-2-thione with NaH in acetonitrile leads to its isomerization into 1-hydroxy-1-methyl-3-thioxo-2,4-diazaspiro[5.5]undecan-7-one followed by the C1-C6 bond cleavage to give <i>N</i>-acetyl-<i>N</i>’-[(2-oxocyclohexyl)methyl]...
| Published in: | Chemistry Proceedings |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-11-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-4583/12/1/3 |