Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

Retinitis pigmentosa (RP) is an inherited retinal disease in which there is a loss of cone-mediated daylight vision. As there are >100 disease genes, our goal is to preserve cone vision in a disease gene-agnostic manner. Previously we showed that overexpressing TXNIP, an α-arrestin protein, p...

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Bibliographic Details
Published in:eLife
Main Authors: Yunlu Xue, Yimin Zhou, Constance L Cepko
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-05-01
Subjects:
Online Access:https://elifesciences.org/articles/90749