Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes

Accumulation of dysfunctional chondrocytes has detrimental consequences on the cartilage homeostasis and is thus thought to play a crucial role during the pathogenesis of osteoarthritis (OA). However, the underlying mechanisms of phenotypical alteration in chondrocytes are incompletely understood. H...

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Bibliographic Details
Published in:eLife
Main Authors: Jana Riegger, Rolf E Brenner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-10-01
Subjects:
Online Access:https://elifesciences.org/articles/91453